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Histocompatibility and Immunogenetics (H&I)

NHSBT Specialist Services H&I laboratories provide a range of diagnostic and reference services to meet the needs of patients and those who treat them.

Our high quality services support the diagnosis and/or treatment of a variety of medical conditions and are relevant in the following clinical areas:

  • Solid organ transplantation and clinical advice for donor selection
  • Haematopoietic stem cell transplantation and clinical advice for donor selection
  • Blood transfusion and transfusion reactions (SHOT)
  • Platelet refractoriness and provision of HLA/HPA selected components
  • Platelet immunology
  • Granulocyte immunology
  • Immunogenetics including diagnostic testing and pharmacogenetics


We are a national network of six laboratories located at NHSBT Birmingham, Colindale, Filton, Newcastle, Sheffield, and Tooting.

To find out more about H&I tests and services see the user guide, contact your H&I laboratory or email HINatnl@nhsbt.nhs.uk



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