NHSBT clinical guidelines

Red cell transfusion and red cell immunohaematology

• Managing patients on monoclonal antibody therapies (PDF 229KB) - for hospital transfusion laboratories, transfusion practitioners and haematology clinical teams: essential information (PDF 408KB)
• Guidelines for the management of urgent red cell transfusion and situations when serological compatibility cannot be assured (PDF 2359KB)
• High titre anti-A/B testing of donors within NHSBT (INF178/4)
• The clinical significance of blood group alloantibodies and the supply of blood for transfusion (PDF 1016KB)
• Selecting appropriate blood products for recipients of ABO / Rh mismatched stem cell transplants (SPN215/2)
• Investigation and clinical management of suspected reactions to IgA (PDF 486KB)
• Investigation and clinical management of patients with a positive  direct antiglobulin test (DAT) with and without haemolysis (SPN220/3)
• Red cell unit for intra uterine transfusion and exchange transfusion with positive direct antiglobulin test (DAT) (SPN564/1.1) 
• Management of D Negative female patients with D Positive: Inadvertent red cell or platelet transfusion; Bone grafts; Solid Organ Transplant (SOT) or large volume Fetomaternal Haemorrhage (FMH) - specification document (PDF 267KB)

Platelet and white cell transfusion, Histocompatibility and Immunogenetics

• Transfusion associated graft versus host disease (PDF 99.5KB)
• Guidelines for the management of platelet transfusion refractoriness (PDF 106KB)
• Transfusion related acute lung injury (TRALI) (PDF 111KB)
• Post transfusion purpura (PDF 73KB)
• Clinical guidelines for the use of granulocyte transfusions (PDF 757KB)
• Neonatal alloimmune thrombocytopenia (NAIT)  (PDF 187KB)
• Thrombasthenia (PDF 70.5KB)

Samples

• RCI sample labelling policy (MPD637/6)
• H&I sample labelling policy (PDF 1602KB)
• Sample packaging policy (DAT2132)

Blood donors with haemochromatosis

We accept individuals with genetic haemochromatosis as blood donors once they are in the maintenance phase of the condition with no associated complications. 

• Donor agreement form (Word 37.5KB) for potential blood donors with haemochromatosis for use by clinicians. It requires the patient’s signature as confirmation of their agreement. Please return the form to the Clinical Support team at your NHSBT centre.
• Leaflet for donors - download 'Haemochromatosis and blood donation' leaflet (PDF 217KB) or order the leaflet
• Information for donors with Haemochromatosis (PDF 217KB)