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Webinar on 3 June 1pm: update on the convalescent plasma trials

Invitation and joining instructions

Non clinical issue for research purposes

NHSBT are in a unique position to supply surplus donated material to the NHS and other authorised external organisations for specific uses including:

  • Research & Development
  • Laboratory Stability/Quality assurance
  • Production/development of biochemical assays & reagents
  • Education & training

We endeavour to minimise waste and process failure in the clinical supply chain however, inevitably there is donated material that is surplus to clinical requirement or unsuitable for therapeutic use.

Non-clinical issues operates on a cost recovery basis. We do not charge for material provided but recovers the costs of making this available. All income is used for the benefit of NHSBT.

NHSBT COVID-19 BioResource

NHSBT and partners have created a bioresource of plasma that can be used for research related to COVID-19. It includes:

  • Plasma donated prior to the coronavirus outbreak (November 2019) which represents a unique set of negative controls
  • Plasma donated by recovered COVID-19 patients*
  • Plasma donated by donors with a positive SARS-CoV-2 antibody test**

 

The bioresource has been established to support the ongoing COVID-19 work related to research for public health benefit. Materials are issued anonymised and only after the application has been reviewed and all aspects of governance are met.

* Plasma donated by recovered COVID-19 patients will contain variable levels of antibodies. High Titre material will be in high demand for hospital patients & not available for non-therapeutic use until sufficient stocks have been established we do not expect this to be before summer 2020

  • Subject to availability, low & medium titre material will be available in limited but increasing volumes from late May
  • These samples will be supplied ambient/frozen in small volumes (< 10 ml)

** Plasma donated by donors with a positive SARS-CoV-2 antibody test will be supplied ambient/frozen in small volumes (<10 ml)

  • Initially all high titre material will be required for hospital patients & not available for non-therapeutic use until sufficient stocks have been established.  We do not expect this to be before summer 2020
  • Subject to availability, low & medium titre material will be available in limited but increasing volumes from late May

Your application will be reviewed by the NHSBT Governance team.

 

Donor consent procedure

The donor consent procedure includes using donated material for:

  • Invitro diagnostic tests & laboratory quality control including EQA schemes
  • Training and education
  • Product / service development of reagents, biochemical assays, new components and procedures
  • Ethically approved research 

Donated material

Donated material shall only be made available to authorised users for specific, approved uses.

All requests to set up a supply of donated bio-material for non clinical use will be considered on a case by case basis to ensure the intended use is appropriate and that:

  • There are no implications for donor health and welfare
  • The supply of material does not impact the clinical supply chain
  • That ethical approval is obtained where appropriate
  • Donors cannot be identified by or linked to a supplied component 

Material is from:

  • Blood and blood components
  • Tissue Services
  • Therapeutic Apheresis Services
  • Cord blood and placenta tissue
  • Anti coagulated / frozen small volume samples
  • HPC (Haemopoietic progenitor cells - Apheresis / bone marrow / cord blood)
  • TC-T (therapeutic cells - T cells)
  • HLA, HPA and HNA Ab +ve and –ve sera (EQA scheme use only)  
Documents

Guide for customers INF965

Application form FRM234 

Contact

Please email your enquiries to nciadmin@nhsbt.nhs.uk