G​uidance for transfusing platelets across blood groups

This has been updated

27 June 2019

Editorial note, 12 September 2022

Please refer to the Platelets page for the current version of this document, or to the NBTC platelet shortage plan on the JPAC website.


This resource provides guidance for hospital transfusion laboratory staff should they need to transfuse platelets across blood groups and describes the circumstances when this is acceptable practice.

Please note, it replaces the resource ‘Appropriate use of platelets across blood groups’.

Jayne Addison - PBM Practitioner