Reporting Adverse Events and Reactions

Actions for transfusion laboratory staff

NHSBT must be informed immediately of all adverse reactions and events.

Documented details should include:

  • the patient involved
  • the type of reaction or event
  • the reason for transfusion
  • the implicated component (including donation number)
  • the contact details of the clinical staff looking after the patient

A serious adverse reaction notification report must also be made as soon as possible via the SABRE (Serious Adverse Blood Reactions and Events) system to both MHRA (Medicines and Healthcare Products Regulatory Agency) and SHOT (Serious Hazards of Transfusion).

Advice on clinical management and investigation of serious adverse reactions can be obtained from the hospital consultant responsible for blood transfusion.

The NHSBT duty consultant for patients must be informed immediately of serious adverse reactions to transfusion that require investigation or involvement by NHSBT. This is particularly important in cases of suspected bacterial contamination because other components may need recall. The duty consultant is reached by contacting your local Hospital Services department.

The request form (published on the request forms page in this section) provides details of the minimum sample requirement.