Temperature excursions

How to find out if units should be retained or discarded in the event of fridge, freezer or incubator failure

Equipment failure from the Red Book on the Tranfusion guidelines website

Exceptionally, ie due to equipment failure at a Blood Centre, red cell components which have been prepared in a closed system and exposed to a core temperature not exceeding 10°C and not less than 1°C may be released for transfusion provided that: 

  • the component has been exposed to such a temperature change on one occasion only (if the unit has not had an excursion within NHSBT, your hospital can follow this guidance to retain blood components following equipment failure)

  • the duration of the temperature change has not exceeded 5 hours 

  • a documented system is available in each Blood Centre to cover such eventualities 

  • adequate records of the incident are compiled and retained
Action for hospitals
  • After quarantining the components, the hospital should call the hospital services department at their local Stock Holding Unit, (SHU) to request a list of PCS13 flagged units. They must specify which report they require: RED CELL, PLATELET or FROZEN component list. Hospitals must provide an email address at the time of the call

  • Hospital services will email the list (in excel format) to the email address provided within 3 hours of the phone call

  • The hospital can use the list to determine if any units have been previously ‘flagged’, in which case they must be discarded
  • The decision to discard or retain any units is the hospitals. If units are retained, obviously a system needs to be in place to record the excursion
  • For more advice (e.g if it’s a product required immediately) we suggest a conversation with your own medic initially

  • If insufficient information is available, our duty consultant may be able to offer advice

  • NHSBT does not require feedback on the units you discard or retain

  • There will be no refund for units that you elect to discard
Limits used to set the PCS13 flag
Blood Component Cold Chain requirements PCS13 flag will be set
Red Cells   Store 2-6 ˚ C  One excursion to 10˚C < 5hrs  allowed
Platelets   20-24 ˚ C  May be set if 18-20˚C  temperature deviation occurs
Frozen Products   < -30 ˚ C  Only if up to -25˚C