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Specialist Therapeutic Services

Specialist Therapeutic Services (STS) provide life-saving and life-enhancing therapeutic apheresis services to adults and children. Patients are either treated in an NHS Blood and Transplant (NHSBT) unit or, when clinically appropriate, hospital.

STS services are delivered across England and North Wales from six therapeutic apheresis units. To make a patient referral or discuss services please contact your local STS consultant or lead nurse.

STS therapeutic apheresis units and contact details

STS is managed by Catherine Howell, Chief Nurse, who is supported by a management team of: Dr Khaled El-Ghariani, Clinical Director STS, Davina Potok, Senior Nurse Manager STS and Claire Thompson, STS Strategy Lead.

 
What services does STS provide?

STS supports a range of clinical specialties including haematology, oncology, nephrology, neurology and rheumatology. Therapeutic procedures include:


Peripheral Blood Stem Cell Collection (PBSC)
Collection of peripheral blood stem cells from either patients or donors, which are used for transplantation. Transplantation is usually required following high dose chemotherapy which destroys a patient’s bone marrow.

Granulocyte Collection
Collection of granulocyte white cells from donors for patients who are neutropenic as a result of treatment prior to or following stem cell transplant and who have infection which is unresponsive to treatment with drugs.

Lymphocyte Collection (DLI)
Collection of lymphocyte white cells from donors who have previously donated bone marrow or peripheral blood stem cells.

Therapeutic Plasma Exchange (TPE)
Removal of disease mediators, excessive/abnormal constituents from plasma or replacement of deficient constituents.

Red Cell Exchange (RCE)
Removal and replacement of a patient’s red blood cells.

Platelet Depletion
Removal of platelets in patients with very high platelet counts due to disease.

White Cell Depletion
Removal of white cells in patients with very high white cell counts due to disease.

Low Density Lipid Removal (LDL)
Removal of LDL cholesterol molecules using filtration technology.

Extracorporeal Photopheresis
An integrated two-stage procedure in which white cells are collected, removed then treated with a photo activated drug and exposed to ultraviolet light before being returned to the patient.

 
Specialist Therapeutic Services Patient and Donor Information

Patient Information: Peripheral Blood Stem Cell Collection (PBSC)
Patient Information: Plasma Exchange Procedure
Patient Information: Red Cell Exchange Procedure
Donor Information: Granulocyte Collection
Donor Information: Peripheral Blood Stem Cell Collection (PBSC)

 

Leaflets can be ordered by email at specialisttherapeuticservices@nhsbt.nhs.uk or by phone: 01865 381037

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