Case Control Study of Intra-Cranial Haemorrhage in Thrombocytopenic Haematology Patients
This study has now closed to recruitment (closed to recruitment June 2015)
What is it?
A national case-control study of intra-cranial haemorrhage in the UK, over a four year period (2011 to 2015), in adult haematology patients who were:
- about to receive or
- just received myeloablative chemotherapy or a stem cell transplant.
This study included all severities of intra-cranial haemorrhage from small asymptomatic haemorrhages, identified only radiologically, to large fatal haemorrhages.
Why is this study important?
- Intra-cranial haemorrhage is a serious but rare complication that occurs in patients with haematological malignancies
- If it occurs it can have devastating consequences (death or major morbidity)
- It is unknown why some patients bleed and others don't
- Risk of significant bleeding is poorly correlated with the platelet count.
Aims of the study
- To identify risk factors for intra-cranial haemorrhage
- To use this information to guide management of patients in the future:
2011 to 2013 newsletters may be obtained from the Study Co-ordinator